Blackpool’s survival hopes suffered a serious blow as Colchester United claimed all three points thanks to Chris Porter’s winner.
The revitalised U’s, who still have feint hopes of avoiding the drop, always looked comfortable once Porter fired beyond Colin Doyle in the second-half.
The result ended Blackpool’s four-game unbeaten run, after David Norris and Danny Philliskirk wasted good chances.
Despite their predicament being worse than Blackpool’s going into the game, Colchester controlled the early exchanges, with Joe Edwards blazing wide after Owen Garvan had missed his kick.
Blackpool’s first opening came from the good craft of Hayden White, who forced his way through down the right and squared for Norris, whose shot came off the heel and went wide.
The returning Elliot Lee was proving a nuisance down the left for Colchester and Doyle needed two attempts to smother his low strike on 22 minutes.
Another former Seasider was between the sticks for the visitors and Elliot Parish comfortably held a bobbling shot from Brad Potts.
It was still United looking the better side and Porter dragged off target just after the half-hour mark, before George Moncur slipped him through to fire over the bar.
Despite the pattern of play, Blackpool ended the half by spurning probably the best chance, as Norris flicked on to Philliskirk, who blew the opening by shooting wide on his left foot.
Half-Time: Blackpool 0 Colchester 0
The break did little to loosen Colchester’s grip on the contest and Porter forced Doyle into a save with his left foot after Gavin Massey had hit the woodwork, before Philliskirk shot at Parish at the other end.
When the opening goal did arrive it was a deserved one for Colchester, as Porter latched onto a lucky ricochet and diverted the ball beyond Doyle.
Porter squandered another opening soon after, before Neil McDonald made a double change, bringing on Jack Redshaw and Bright Osayi-Samuel for Mark Cullen and Philliskirk.
It was still Colchester impressing though and Lee flashed an effort across goal on 70 minutes. Not long after Liam Smith took the place of Potts and McAlister headed at Parish.
That was the final half-chance of the contest as Blackpool were beaten at home, ending their recent good run of form.
Full-Time: Blackpool 0 Colchester 1