Blackpool will look to take three points from former-boss Ian Holloway and finally get the ball rolling on the new campaign this weekend.
The Seasiders are without a point from their opening four league games, and now face a Millwall side rejuvenated under Holloway.
José Riga’s Blackpool side have lost by a single goal on all but one occasion this season, including in a narrow defeat to Wigan last time out.
By contract, The Lions have taken seven points from their first four games, but have lost their last two, both on home soil.
Both teams narrowly avoided the drop last season, and Blackpool prevailed the last time they met in March at Bloomfield Road.
Andrea Orlandi is expected to return for Pool, having come through an hour of Lancashire Senior Cup action this week.
Riga also plans to have Joan Oriol available despite tiredness, but will wait on the fitness of Steve Davies.
Gary MacKenzie is still hampered by injury so will miss the trip, along with Jacob Mellis and Bobby Grant.
As for Millwall, they could hand a debut to Mathias Ranegie, who joined on loan from Watford on Thursday.
Nicky Bailey will miss out with a calf problem and Ed Upson remains doubtful with a hamstring injury.
In The Build-Up
The Seasiders were beaten 1-0 at Wigan last week, but have had a free week, aside from the Lancashire Senior Cup, to prepare for the Millwall clash.
The Lions were in Capital One Cup action this week, but their young side was beaten by Premier League Southampton.
Last weekend Holloway’s men were beaten 1-0 at home to Rotherham United.
The last time the pair met was at Bloomfield Road in March as Ricardo Fuller, ironically now of Millwall, headed home the only goal.
At The Den last season Millwall were victorious, cancelling out Tom Ince’s opener in a 3-1 win.
Around The Championship
Nottingham Forest take their unbeaten record to Hillsborough in Saturday’s early kick-off.
Managerless Leeds host Bolton, while Fulham and Cardiff, both recently relegated, meet at Craven Cottage.
Sheffield Wed v Nottingham Forest (12:15)
Brighton v Charlton
Derby v Ipswich
Fulham v Cardiff
Leeds V Bolton
Middlesbrough v Reading
Norwich v Bournemouth
Rotherham v Brentford
Watford v Huddersfield
Wigan v Birmingham
Wolves v Blackburn